Opportunity Information: Apply for RFA DA 19 036
The HEAL Initiative: HEALthy Brain and Child Development Study (HEALthy BCD) funding opportunity (RFA-DA-19-036) is an NIH discretionary grant mechanism using the R34 planning/feasibility grant format, with clinical trials not allowed. It is led by the National Institute on Drug Abuse (NIDA) in coordination with several NIH Institutes, Centers, and Programs including NIAAA, NICHD, NIMH, NIMHD, NINDS, and the ECHO program. The central purpose is to support projects that propose, refine, and test the feasibility of research study designs that can ultimately be used to understand how substance exposure before birth and after birth influences child outcomes over time. The emphasis is on building strong, workable approaches that can later scale into a larger, coordinated multi-site effort focused on early brain development and related health trajectories.
The scientific scope is broad and intentionally reflects real-world patterns of substance use and co-use. Applicants are asked to address the impact of prenatal and postnatal exposure to substances such as opioids and opioid treatment medications, cannabis, alcohol, tobacco, and other prescription or illicit drugs, whether these exposures occur alone or in combination. The outcomes of interest span brain development as well as social and behavioral development, with explicit attention to downstream risks such as mental illness and later substance use. In practice, this means the planning and feasibility work could include developing recruitment and retention strategies for pregnant people and families, piloting measurement batteries for neurodevelopmental, behavioral, and social outcomes, assessing data collection workflows, and determining whether proposed designs can capture timing, dosage, and patterns of exposure alongside important contextual factors (for example, caregiving environment, stress, socioeconomic conditions, and access to treatment).
A key deliverable expectation is that awardees will not only test whether their study designs are workable, but also actively contribute to early network-building for what is intended to become a broader HEALthy BCD research enterprise. The opportunity specifically notes participation in several grantee meetings where teams share lessons learned, align around emerging best practices, and begin shaping the eventual network of sites needed to conduct the larger study. This collaborative component signals that NIH is looking for applicants who can contribute to standardization and coordination across future sites, such as harmonizing measures, improving comparability of data, and identifying practical solutions to common challenges like enrolling participants with varying patterns of polysubstance exposure.
Eligibility is wide and includes many types of U.S.-based organizations and governmental entities. Eligible applicants include state, county, city or township governments, special district governments, and independent school districts, along with public and state-controlled institutions of higher education and private institutions of higher education. Tribal eligibility includes federally recognized Native American tribal governments as well as tribal organizations that are not federally recognized, and the announcement also highlights categories such as Alaska Native and Native Hawaiian Serving Institutions, AANAPISI institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs). Nonprofit organizations are eligible whether or not they hold 501(c)(3) status, and for-profit organizations (other than small businesses) and small businesses are also listed as eligible. Faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions are included as well.
At the same time, there are clear restrictions related to foreign involvement. Non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply, non-domestic components of U.S. organizations are not eligible, and foreign components as defined by the NIH Grants Policy Statement are not allowed. In other words, the work supported under this R34 must be fully domestic in terms of applicant organization and project components.
From an administrative standpoint, the opportunity is cataloged under multiple CFDA numbers (93.113, 93.242, 93.273, 93.279, 93.307, 93.853, 93.865), reflecting the multi-institute participation. The original posting shows a creation date of December 21, 2018, and an original closing date of March 25, 2019. The listed award ceiling is $225,000, which is consistent with a planning and feasibility award intended to support design work, piloting, and coordination activities rather than full-scale longitudinal data collection. Overall, the grant is best understood as a front-end investment by NIH to ensure that the eventual HEALthy BCD study is built on study designs that are realistic, rigorously developed, and ready to scale into a coordinated network capable of answering high-impact questions about early-life substance exposure and child development.Apply for RFA DA 19 036
- The National Institutes of Health in the education, environment, health, income security and social services sector is offering a public funding opportunity titled "HEAL Initiative: HEALthy Brain and Child Development Study (HEALthy BCD) ( R34- Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.242, 93.273, 93.279, 93.307, 93.853, 93.865.
- This funding opportunity was created on 2018-12-21.
- Applicants must submit their applications by 2019-03-25. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $225,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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