Successor-in-Interest (Type 6 Parent Clinical Trial Optional) | PA 24 253

Opportunity Information: Apply for PA 24 253

The NIH funding opportunity titled "Successor-in-Interest (Type 6 Parent Clinical Trial Optional)" (PA 24-253) is not a traditional grant competition for new research or program funding. Instead, it is an administrative pathway for organizations that already hold certain NIH awards (the specific eligible award types are listed in the full FOA) to request a formal change in the recipient organization on an existing grant. In practical terms, this is used when an NIH-funded project needs to be transferred from the current awardee institution to a different institution because of an organizational change, such as a merger, acquisition, reorganization, or other situation where a new legal entity is taking over the responsibilities of the current recipient. The NIH refers to these transfers as "Successor-in-Interest" actions, and they are treated as prior approval requests under the NIH Grants Policy Statement (specifically the prior approval section referenced in the announcement).

Applications submitted under this notice of funding opportunity are routed directly to the Grants Management Specialist associated with the existing award rather than going through a typical peer review process. The emphasis is on administrative and compliance review: NIH is evaluating whether the new organization can legally and programmatically assume the grant, whether the proposed transfer protects the government’s interests, and whether the project can continue without disruption while meeting all NIH requirements. A key point in the announcement is that submitting a successor-in-interest request does not guarantee the award will be transferred. NIH retains full discretion to approve or deny the request, and applicants are strongly encouraged to discuss any potential transfer in advance with the awarding NIH Institute or Center to reduce the chance of surprises during review.

Eligibility is broad in the sense that many types of entities can potentially be involved as the proposed new recipient, so long as the underlying award is one of the grant mechanisms NIH allows for this process. Eligible applicant categories include state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; Native American tribal governments (federally recognized) and other tribal organizations; public housing authorities; nonprofits (both 501(c)(3) and non-501(c)(3)); for-profit organizations (other than small businesses); small businesses; and other entities. NIH also explicitly notes additional categories often associated with serving specific communities or operating in specific jurisdictions, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), faith-based or community-based organizations, eligible federal agencies, regional organizations, U.S. territories or possessions, and even non-U.S. (foreign) organizations where applicable. The takeaway is that NIH is not limiting this administrative action to a narrow slice of institutions; the main constraint is whether the current NIH award type is eligible and whether the transfer meets NIH policy and oversight standards.

From a timing and planning standpoint, the opportunity remains open for several years, with an original closing date listed as July 17, 2027, reflecting that successor-in-interest requests arise as needed rather than on a single annual cycle. The listing does not provide an award ceiling or an expected number of awards because this mechanism is not intended to create new awards; it facilitates the continuation of already-funded projects under a different recipient organization when justified and approved. The opportunity is housed under NIH and spans a wide range of CFDA (Assistance Listing) numbers across many NIH programs, reinforcing that the process can apply to many different NIH funding areas so long as the specific grant mechanism qualifies.

Overall, PA 24-253 is best understood as NIH’s formal submission route for an institution-to-institution transfer of an existing NIH grant due to a change in organizational status. The central purpose is continuity and accountability: ensuring the project can proceed, the responsible legal entity is correctly reflected in NIH records, and the new organization can meet all administrative, financial, and compliance obligations tied to the award. The most important practical advice embedded in the notice is to coordinate early with the awarding Institute or Center and the assigned Grants Management Specialist, because approval is not automatic and NIH will scrutinize whether the transfer is appropriate and protects the integrity of the award.

• The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Successor-in-Interest (Type 6 Parent Clinical Trial Optional)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.142, 93.143, 93.172, 93.173, 93.213, 93.233, 93.242, 93.273, 93.279, 93.286, 93.307, 93.310, 93.350, 93.351, 93.352, 93.353, 93.361, 93.393, 93.394, 93.395, 93.396, 93.397, 93.398, 93.399, 93.837, 93.838, 93.839, 93.840, 93.846, 93.847, 93.853, 93.855, 93.859, 93.865, 93.866, 93.867, 93.879.
• This funding opportunity was created on 2024-07-11.
• Applicants must submit their applications by 2027-07-17.
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

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